What is Postpartum Hemorrhage (PPH)?

After childbirth, some bleeding is natural. But when it becomes excessive, it can turn life-threatening within minutes.
This condition is called Carboprost Injection PPH — defined as blood loss of more than 500 mL after vaginal delivery or 1000 mL after a cesarean section.

PPH remains one of the leading causes of maternal deaths worldwide — yet it’s one of the most preventable with timely medical care and awareness.
That’s where Carboprost Injection PPH plays a vital role — helping doctors control excessive bleeding and save lives.

Why the Uterus Must Contract After Delivery

The most common reason for postpartum bleeding is uterine atony, when the uterus fails to contract effectively after childbirth.

Normally, strong uterine contractions help compress blood vessels and stop bleeding.
But if those contractions are weak or absent, the vessels stay open — leading to rapid blood loss.

Risk factors include:

• Overdistended uterus (large baby, twins, or excess amniotic fluid)

• Prolonged or very quick labor

• Retained placental tissue

• Use of medications that relax uterine muscles

• Fatigue or exhaustion of uterine muscles

When this occurs, Carboprost Injection PPH can stimulate powerful contractions to restore uterine tone and control hemorrhage.

What Is Carboprost Injection PPH?

Carboprost Injection PPH contains Carboprost Tromethamine, a synthetic analogue of prostaglandin F₂α — a natural substance that helps the uterus contract.

When administered by injection, Carboprost acts directly on the uterine smooth muscles to produce strong and sustained contractions.
These contractions help:

• Compress uterine blood vessels

• Reduce ongoing bleeding

• Expel retained tissue

• Restore uterine tone

It is especially effective when first-line agents such as oxytocin or methylergometrine fail.

Introducing Gy-Prost 125 / 250

Under its Gynecology segment, Quinek Life Sciences introduces Gy-Prost Injection (125 µg & 250 µg) — a trusted Carboprost Injection PPH formulation for effective control of postpartum bleeding.

Each mL contains:

• Carboprost Tromethamine 125 µg or 250 µg (depending on variant)

For intramuscular use under medical supervision only.

Key Features:

• Consistent uterine response

• Rapid onset of action

• Reliable bleeding control in refractory PPH cases

When Is Carboprost Injection PPH Used?

Indications:

• Control of postpartum hemorrhage due to uterine atony when other uterotonics (like oxytocin or ergometrine) are ineffective

• Therapeutic termination of pregnancy (as per medical guidelines)

Dosage & Administration:

• Given intramuscularly by a qualified healthcare professional

• Dose depends on clinical condition and response

• Continuous monitoring required during treatment

How Carboprost Injection PPH Works

Carboprost binds to prostaglandin receptors in the uterine smooth muscle →
Increases intracellular calcium → triggers strong uterine contractions → compresses bleeding vessels → reduces blood flow → controls hemorrhage.

In simpler terms, Carboprost Injection PPH helps the uterus “clamp down” when it fails to contract naturally — preventing dangerous blood loss.

Benefits of Gy-Prost 125 / 250

Rapid bleeding control: Acts within minutes after intramuscular injection.
Effective in refractory PPH: Works even when oxytocin or ergot derivatives fail.
Prevents surgical interventions: Reduces need for procedures like hysterectomy.
Restores uterine tone quickly: Helps stabilize the mother post-delivery.
Clinically proven: Reliable safety and consistent results.

Safety and Precautions

Carboprost Injection PPH should be administered only in a hospital or maternity care setting by trained professionals.

Precautions:

• Monitor blood pressure, pulse, and uterine tone

• Use cautiously in patients with asthma, cardiac, renal, or hepatic disorders

• Avoid in patients with prostaglandin hypersensitivity

• Keep emergency care readiness available

Common temporary effects: Nausea, vomiting, flushing, mild fever — generally self-limiting.

Carboprost Injection PPH — A Lifesaving Role

Every minute counts during postpartum hemorrhage.
When the uterus fails to contract, Carboprost Injection PPH helps restore uterine tone, stop bleeding, and save lives.

By enabling doctors to act swiftly, Gy-Prost has become an essential component of advanced obstetric care — reflecting Quinek Life Sciences’ dedication to maternal wellbeing.

Quinek Life Sciences: Supporting Safe Motherhood

At Quinek Life Sciences, our mission extends beyond pharmaceuticals.
We create awareness, accessibility, and trust through every formulation.

Carboprost Injection PPH (Gy-Prost 125 / 250) is designed for:

• Safer deliveries

• Faster recovery

• Stronger maternal outcomes

We stand for:

• Affordable specialty medicines

• Transparent healthcare

• Education that saves lives

Our promise: “Wishing for Wellbeing.”

Key Facts at a Glance

Final Thought

Childbirth is powerful — but sometimes, even nature needs help.
With Carboprost Injection PPH, doctors have a dependable partner to restore uterine tone, prevent hemorrhage, and protect a mother’s life.

At Quinek Life Sciences, we believe that saving a mother means saving a family, a generation, and a future.

Wishing for Wellbeing,
Team Quinek Life Sciences